Technology Readiness Levels (TRLs) what are they and how are they used in grants?

Technology Readiness Levels (TRLs) are the shorthand of grant applications, but how do I apply them to my tech if its non-engineering e.g. SaaS / MedTech / Pharma?

TRLs are the short hand of grants – they are used all over the scope documentation to describe what kind of projects the awarding bodies are looking to fund.

๐—ช๐—ต๐˜† – TRLs provide an instant snapshot of risk, investment needs, and timeline expectations – regardless of the underlying ๐˜๐—ฒ๐—ฐ๐—ต๐—ป๐—ผ๐—น๐—ผ๐—ด๐˜† ๐˜€๐—ฒ๐—ฐ๐˜๐—ผ๐—ฟ.

When someone says “we’re at TRL 4,” you immediately understand they’ve proven their concept works in a lab but still need significant development before commercialization.

๐—ฆ๐—ผ ๐˜„๐—ต๐—ฎ๐˜ ๐—ฎ๐—ฟ๐—ฒ ๐˜๐—ต๐—ฒ๐˜† ๐—ฎ๐—ป๐—ฑ ๐—ต๐—ผ๐˜„ ๐—ฑ๐—ผ๐—ฒ๐˜€ ๐˜๐—ต๐—ถ๐˜€ ๐—ต๐—ฒ๐—น๐—ฝ

In short the scale has 3 principal groupings:

TRL 1-3: Concept & Research Phase:
Early stage idea -> proven concept

TRL 4-6: Development & Validation:
Prototype development -> Proven in a relevant environment

TRL 7-9: Deployment & Commercial Readiness:
Late stage development -> Final product in operational environment.

๐—•๐˜‚๐˜ ๐—ต๐—ผ๐˜„ ๐—ฑ๐—ผ ๐˜„๐—ฒ ๐˜๐—ฎ๐—ธ๐—ฒ ๐˜๐—ต๐—ถ๐˜€ ๐˜€๐—ฐ๐—ฎ๐—น๐—ฒ ๐˜๐—ผ ๐—บ๐—ฒ๐—ฑ๐—ถ๐—ฐ๐—ฎ๐—น ๐—ผ๐—ฟ ๐˜€๐—ผ๐—ณ๐˜๐˜„๐—ฎ๐—ฟ๐—ฒ?

Neither of these fields neatly fit on the above framework, so some creative wiggling needs to be undertaken.

๐— ๐—ฒ๐—ฑ๐—ถ๐—ฐ๐—ฎ๐—น ๐—ฅ๐—ฒ๐˜€๐—ฒ๐—ฎ๐—ฟ๐—ฐ๐—ต ๐—ง๐—ฟ๐—ฎ๐—ป๐˜€๐—น๐—ฎ๐˜๐—ถ๐—ผ๐—ป:

For medical devices or pharma – it’s best to think in terms of clinical trials:

TRL 1-3: Target identification, in vitro testing, pre-clinical research
TRL 4-5: Component validation, pre-clinical trials
TRL 6: First human trials (Phase I) or safety demonstrations for devices
TRL 7: Phase II clinical trials or operational prototype testing
TRL 8: Phase III clinical trials or system qualification
TRL 9: Market-approved product ready for commercialization

๐—ฆ๐—ผ๐—ณ๐˜๐˜„๐—ฎ๐—ฟ๐—ฒ/๐—ฆ๐—ฎ๐—ฎ๐—ฆ ๐—ง๐—ฟ๐—ฎ๐—ป๐˜€๐—น๐—ฎ๐˜๐—ถ๐—ผ๐—ป:

For SaaS its better to translate the Alpha/Beta framework

TRL 1-3: Concept research through early prototype development
TRL 4: Alpha testing with integrated components
TRL 5: System validation in realistic environment
TRL 6: Beta version ready for user testing
TRL 7: Final prototype testing in operational setting
TRL 8: Pre-commercial demonstration with real users
TRL 9: Commercial product deployment with full functionality

Using these scales – it will allow you to understand where you are on the traditional development framework – and most importantly which grants are the best fit for your development right now.

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